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Top Song(s)
• Ke$ha - Tik-Toc
• Bruno Mars - Just the Way You Are
• Rihanna - Only girl (in the world)
• Taio Cruz - Dynamite
• Owl City - Fireflies
Top Film(s)
• Inception
• The Social Network
• Toy Story 3
• Scott Pilgrim vs. the World
• Black Swan
Best Selling Book(s)
• Mockingjay - Suzanne Collins
• Spirit Bound - Richelle Mead
• Clockwork Angel - Cassandra Clare
• Room - Emma Donoghue
• Last Sacrifice - Richelle Mead
Famous Deaths
• January 11 - Miep Gies, Dutch discoverer of Anne Frank's diary
• February 18 - John Babcock, Last known Canadian veteran of World War I
• March 5 - Edgar Wayburn, American environmentalist awarded Presidential Medal of Freedom 1999
• April 5 - Vitali Sevastiyanov, Soviet cosmonaut (Soyuz 9, 18)
• May 27 - John William Finn, American US Navy sailor, awarded the 1st Medal of Honor of WWII
• June 26 - Algirdas Brazauskas, President of Lithuania
• August 12 - Guido de Marco, 6th president of Malta, 45th President of the United Nations General Assembly
• October 7 - Milka Planinc, Prime Minister of Yugoslavia (1982-86)
• November 3 - Viktor Chernomyrdin, Russian politician (Prime Minister of Russia)
• December 25 - Carlos Andrés Pérez, President of Venezuela (1974-79, 89-94)
Medical/Science/Technology
• British scientists report that they have made artificial arteries out of flexible polymer.
• A joint American-Australian team construct a quantum computer that can correctly simulate a hydrogen molecule.
• Scientists announce that they are on the verge of creating pills that target specific genes in the human genome to increase longevity.
• Scientists use direct fossil evidence to make a reasonable interpretation of a dinosaur's color.
• The European-owned Paranal Observatory in Chile provides new images of the Orion Nebula.
• Researchers discover the reasons behind malformed limbs in embryos exposed to thalidomide.
• Scientists discover several genes linked to stuttering, hoping leading to a possible enzyme treatment for the condition.
• Iranian researchers develop a silica-based nano-absorbent to filter harmful heavy metals from waste water.
• The first known animals to live their lives entirely without oxygen are members of the phylum Loricifera.
• Scientists create robotic nano-spiders – microscopic DNA constructs able to follow programmed instructions.
Political
• January 14 – President Barack Obama commits $100,000,000 to help Haiti recover from the 2010 earthquake.
• January 16 – Secretary of State Hillary Clinton and USAID Director Rajiv Shah travel to Haiti.
• January 25 – President Barack Obama hosts the Los Angeles Lakers at the White House.
• January 27 – President Barack Obama in his first State of the Union Address emphasizes the nation's economy, job creation.
• February 18 - President Barack Obama issues Executive Order 13531.
• February 23 – The United States Navy officially announces that it will end its ban of women in submarines.
• March 21 – The United States House of Representatives passes the Patient Protection and Affordable Care Act.
• March 23 - President Barack Obama signs the Patient Protection and Affordable Care Act into law.
• April 15 – President Barack Obama delivers a major speech on the future of NASA's human spaceflight program.
• April 23 – Arizona Governor Jan Brewer signs the Support Our Law Enforcement and Safe Neighborhoods Act.
National
• January 2 – North Carolina bans smoking in bars, restaurants, public places, and vehicles.
• January 13 - Google announces that they were the target of a cyber attack from China.
• February 2 – The Air Force Academy in Colorado Springs opens a worshipping site for earth-centered religions.
• February 8 – The 100th anniversary of the Boy Scouts of America.
• March 3 – The District of Columbia's same-sex marriage law goes into effect.
• April 1 – Official tabulation of the 2010 US Census begins.
• April 13 - Georgia becomes the 17th state to sue the federal government over the Patient Protection and Affordable Care Act.
• May 1 – 2010 Times Square car bombing attempt: Car bomb fails to go off in Times Square, New York City.
• June 18 - The Protecting Cyberspace as a National Asset Act is introduced in the US Senate.
• August 4 - Forty U.S. billionaires announce plans to give half of their wealth to charitable organizations.
Worldwide
• January 12 – A 7.0 magnitude earthquake occurs in Haiti, devastating the nation's capital, Port-au-Prince.
• February 10 – The Australian government is hit by cyberattacks from freedom of expression activists.
• March 16 – The Kasubi Tombs, Uganda's only cultural World Heritage Site, are destroyed by fire.
• May 1 – Expo 2010 is held in Shanghai, China.
• June 10 – 14 – Ethnic riots in Kyrgyzstan between Kyrgyz and Uzbeks result in the deaths of hundreds.
• July 21 – Slovenia becomes the 32nd member of the OECD.
• August 16 – AIRES Flight 8250, A Boeing 737–700, crashed on landing at San Andrés, Colombia.
• October 3 – Germany makes final reparation payment for World War I.
• November 20 – Participants of the 2010 NATO Lisbon summit issue the Lisbon Summit Declaration.
• December 17 – The attempted suicide of Mohamed Bouazizi, a street vendor in Tunisia, triggers the Tunisian Revolution.