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Top Song(s)
• The Rolling Stones - (I Can't Get No) Satisfaction
• The Righteous Brothers - Unchained Melody
• The Beatles - Help!
• The Temptations - My Girl
• Bob Dylan - Like a Rolling Stone
Top Film(s)
• For a Few Dollars More
• Repulsion
• Red Beard
• Doctor Zhivago
• Thunderball
Best Selling Book(s)
• Dune - Frank Herbert
• A Charlie Brown Christmas - Charles M. Schulz
• Hotel - Arthur Hailey
• In Cold Blood - Truman Capote
• The Autobiography of Malcolm X - Malcolm X
Famous Deaths
• January 4 – T. S. Eliot, American-British poet, Nobel Prize laureate
• February 6 – Frederick, Prince of Hohenzollern
• March 13 - Fan Noli, Albanian bishop, poet and politician, 13th Prime Minister of Albania
• May 6 – Oren E. Long, American politician, 10th Governor of Hawai'i
• June 5 - Eleanor Farjeon, British author of children's literature
• July 7 – Moshe Sharett, 2nd Prime Minister of Israel
• August 13 – Hayato Ikeda, Japanese politician, 38th Prime Minister of Japan
• September 8 - Hermann Staudinger, German chemist, Nobel Prize laureate
• October 12 – Samir Al-Rifai, 6-time Prime Minister of Jordan
• November 18 - Henry A. Wallace, 33rd Vice President of the United States
Medical/Science/Technology
• The "brain-eating amoeba" Naegleria fowleri is detected for the first time.
• The Parma wallaby, thought for around 70 years to be extinct, is rediscovered on Kawau Island.
• Kevlar high-strength para-aramid synthetic fiber is developed by Stephanie Kwolek at DuPont.
• Wang Yinglai and colleagues perform the first successful synthesis of insulin.
• CDC 6600 supercomputer delivered to CERN in Geneva.
• Lotfi Zadeh develops fuzzy logic.
• English pediatrician Harry Angelman first describes Angelman syndrome.
• English neurologist Victor Dubowitz first describes Dubowitz syndrome.
• Frank Pantridge installs the first portable defibrillator, in a Belfast ambulance.
• Patent for the lava lamp filed.
Political
• January 4 – President Lyndon B. Johnson proclaims his "Great Society" during his State of the Union Address.
• January 20 – President Lyndon B. Johnson begins his full term.
• March 15 – President Lyndon B. Johnson makes his "We Shall Overcome" speech.
• March 18 – A United States federal judge rules that the (SCLC) has the lawful right to march to Montgomery, Alabama.
• April 28 – U.S. troops are sent to the Dominican Republic by President Lyndon B. Johnson.
• July 28 – President Lyndon B. Johnson announces his order to increase the number of United States troops in South Vietnam.
• July 30 – President Lyndon B. Johnson signs the Social Security Act of 1965 into law, establishing Medicare and Medicaid.
• August 6 – President Lyndon B. Johnson signs the Voting Rights Act of 1965 into law.
• August 31 – President Johnson signs a law penalizing the burning of draft cards with up to 5 years in prison and a $1,000 fine.
• October 3 – President Lyndon B. Johnson signs an immigration bill which abolishes quotas based on national origin.
National
• February 21 – Malcolm X is assassinated by three members of the Nation of Islam in Manhattan.
• March 7 – Bloody Sunday: Some 200 Alabama State Troopers clash with 525 civil rights demonstrators in Selma, Alabama.
• Match 21 - Martin Luther King Jr. leads 3,200 Civil rights activists in a march from Selma, Alabama, to Montgomery.
• March 23 – Gemini 3: NASA launches the United States' first 2-person crew into Earth orbit.
• May 6 – A tornado outbreak near the Twin Cities in Minnesota kills 13 and injures 683.
• June 3 – Gemini 4: Astronaut Ed White makes the first U.S. space walk.
• July 14 – U.S. spacecraft Mariner 4 flies by Mars, becoming the first spacecraft to return images from the Red Planet.
• August 11 – The Watts Riots begin in Los Angeles, California.
• August 15 – The Beatles perform the first stadium concert in the history of rock, playing at Shea Stadium in New York City.
• October 4 - Pope Paul VI visits the United States.
Worldwide
• January 30 – The state funeral of Sir Winston Churchill takes place in London with the largest assembly of dignitaries in the world.
• February 18 – The Gambia becomes independent from the United Kingdom.
• March 8 – Some 3,500 United States Marines arrive in South Vietnam, becoming the first American combat troops in Vietnam.
• March 18 – Cosmonaut Alexei Leonov leaves his Voskhod 2 spacecraft for 12 minutes, becoming the first person to walk in space.
• April 9 – The West German parliament extends the statute of limitations on Nazi war crimes.
• June 1 – A coal mine explosion in Fukuoka, Japan, kills 237.
• August 30 – An avalanche buries a dam construction site at Saas-Fee, Switzerland, killing 90 workers.
• September 2 - Pakistani troops enter the Indian sector of Kashmir, while Indian troops counter at Lahore.
• October 7 – Seven Japanese fishing boats are sunk off Guam by Super Typhoon Carmen; 209 are killed.
• December 5 - Charles de Gaulle is re-elected as French president with 10,828,421 votes.