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Top Song(s)
• Hoagy Carmichael - Stardust
• Gene Austin - My Blue Heaven
• Duke Ellington - Black & Tan Fantasy
• Frankie Trumbauer - Singin' the Blues
• Bix Beiderbecke - In a Mist
Top Film(s)
• Sunrise: A Song of Two Humans
• Metropolis
• Napoléon
• Wings
• The Unknown
Best Selling Book(s)
• Steppenwolf - Hermann Hesse
• To the Lighthouse - Virginia Woolf
• Now We Are Six - A.A. Milne
• Archy and Mehitabel - Don Marquis
• Amerika - Franz Kafka
Famous Deaths
• January 17 – Juliette Gordon Low, founder of the Girl Scouts USA
• February 6 – Mateo Correa Magallanes, Mexican Roman Catholic priest, martyr and saint
• March 4 – Ira Remsen, American chemist, discoverer of saccharin
• May 8 - Charles Nungesser, French aviator, World War I fighter ace
• June 1 - Lizzie Borden, American woman accused and acquitted of parricide
• June 9 - Victoria Woodhull, American feminist, spiritualist and first woman to ever run for U.S. President
• August 13 – James Oliver Curwood, American writer and conservationist
• September 5 - Wayne Wheeler, American temperance movement leader
• September 29 - Willem Einthoven, Dutch inventor, recipient of the Nobel Prize
• October 29 – Hermann Muthesius, German architect, author and diplomat
Medical/Science/Technology
• Edward Emerson Barnard's A Photographic Atlas of Selected Regions of the Milky Way is published posthumously.
• Fritz London and Walter Heitler apply quantum mechanics to explain covalent bonding in the hydrogen molecule.
• Carbon emissions from fossil fuel burning and industry reach one billion tons per year.
• American biologist Raymond Pearl publishes an influential attack on the basic assumptions of eugenics.
• Publication of the 2nd edition of Principia Mathematica by Alfred North Whitehead and Bertrand Russell.
• Antonio Egas Moniz develops cerebral angiography.
• Ronald Canti's stop-motion cinematic technique illustrates the microscopic behavior of cells.
• German theoretical physicist Werner Heisenberg writes a letter to fellow physicist Wolfgang Pauli.
• American electrical engineer Harold Stephen Black invents the negative-feedback amplifier.
• Completion of a bridge by Westinghouse Electric and Manufacturing in Turtle Creek, Pennsylvania.
Political Events
• January 17 – Bibb Graves is sworn in as the 38th governor of Alabama replacing William W. Brandon.
• January 24 – U.S. Marines invade Nicaragua by orders of President Calvin Coolidge, intervening in the Nicaraguan Civil War.
• February 23 – The U.S. Federal Radio Commission begins to regulate the use of radio frequencies.
• April 12 - The Royal and Parliamentary Titles Act 1927 renames the United Kingdom of Great Britain and Ireland as the United Kingdom.
• May 2 – Buck v. Bell decided in the Supreme Court of the United States, permitting compulsory sterilization of people with intellectual disability.
• May 9 – The Australian Parliament convenes for the first time in Canberra, Australian Capital Territory.
• May 20 – By the Treaty of Jeddah, the United Kingdom recognizes the sovereignty of Ibn Saud.
• July 1 – The Food, Drug, and Insecticide Administration (FDIA) is established as a United States federal agency.
• August 2 - U.S. President Calvin Coolidge announces, "I do not choose to run for president in 1928."
• September 25 – A treaty signed by the League of Nations Slavery Commission abolishes all types of slavery.
National Events
• January 7 – The first transatlantic telephone call is made from New York City to London.
• April 22–May 5 – The Great Mississippi Flood of 1927 affects 700,000 people.
• April 30 – The Federal Industrial Institute for Women opens near Alderson, West Virginia.
• May 11 – The Academy of Motion Picture Arts and Sciences, the "Academy" in "Academy Awards," is founded.
• May 17 – Army aviation pioneer Major Harold Geiger dies in the crash of his Airco DH.4 de Havilland plane.
• May 18 – Bombings by a disaffected local official result in 45 deaths, mostly children, in Bath Township, Michigan.
• May 20–21 – Aviator Charles Lindbergh makes the first solo non-stop trans-Atlantic flight, from New York to Paris.
• May 26 – The final Model T rolls off the assembly line at the Ford Motor Company factory in Highland Park, Michigan.
• October 28 – Pan American Airways' first flight takes off from Key West, bound for Havana.
• October 4 – Carving of the sculptures at Mount Rushmore, South Dakota begins.
Worldwide Events
• January 9 – The Laurier Palace Theatre fire at a movie theatre in Montreal, Quebec, Canada, kills 78 children.
• February 7 – An attempted military coup in Lisbon, Portugal, is successfully put down.
• February 19 - A general strike takes place in Shanghai in protest against the presence of British troops.
• April 27 - The Carabineros de Chile (Chilean national police force and gendarmery) are created.
• May 12 – British police officers raid the office of the Soviet trade delegation in London.
• May 24 – The United Kingdom cuts its diplomatic relations with the Soviet Union due to revelations of espionage.
• June – The volcanic island of Anak Krakatau begins to form in the Sunda Strait of Indonesia.
• July 11 – The 1927 Jericho earthquake strikes Palestine, killing around 300 people.
• October 9 – The Mexican government crushes a rebellion in Veracruz.
• November 12 - Mahatma Gandhi makes his only visit to Ceylon.